BDNF (Brain-Derived Neurotrophic Factor)

What Is BDNF?
Brain-derived neurotrophic factor, or BDNF, is a member of the neurotrophin family of signaling proteins. It is produced in the nervous system and other tissues and participates in neuronal survival, differentiation, synaptic regulation, and activity-dependent plasticity. BDNF primarily signals through the TrkB receptor, while precursor and mature forms may interact differently with TrkB and the p75 neurotrophin receptor.
Although BDNF is widely studied as a biological factor and potential biomarker, associations between BDNF levels and health conditions do not establish that externally administered BDNF would produce a clinical benefit.
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Current Research
Research has examined BDNF in neurodevelopment, learning, synaptic plasticity, exercise physiology, psychiatric research, and neurodegenerative disorders
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