SS-31 (Elamipretide)

What Is SS-31?
SS-31 is the research designation for elamipretide, a synthetic four-amino-acid peptide designed to concentrate within mitochondria.
Research has examined its interactions with the inner mitochondrial membrane and cardiolipin, a phospholipid involved in membrane organization and energy production. Elamipretide has been evaluated in several clinical development programs involving mitochondrial and cardiovascular disorders.
In 2025, the FDA granted accelerated approval to a specific elamipretide formulation under the brand name Forzinity for certain patients with Barth syndrome.
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Current Research
Research has focused on mitochondrial membranes, cardiolipin biology, oxidative phosphorylation, cellular energetics, and disorders involving mitochondrial dysfunction.
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